FAQ & MYTHS

SOURCES OF REPARATIVE CELLS FOR REGENERATIVE THERAPIES Cellular therapy and regenerative biomolecules reside within the cells of many tissues of the human body and for therapeutic grafting are sourced in two ways.

Autograft Tissue sourcing:

-THE AMAZING REGENERATIVE POWER OF ADIPOSE TISSUE (FAT source).

• Among other functions, adipose plays a major role in the healing or reparative process. Adipose contains a high concentration of specialized reparative cells, which are used in cellular therapy. Adipose also provides cushioning and support to assist the healing process and may help reduce damage from injury, aging, or degeneration of human tissue.

BONE MARROW ASPIRATE SOURCE

• Bone marrow is sometimes used as a source for regenerative procedures; however, it may contain a lower concentration of reparative cells compared with adipose tissue. Additionally, bone marrow extraction is generally considered more invasive and may cause more discomfort than minimally invasive fat tissue extraction.

Perinatal Tissue Science

• Flowable Amniotic Tissue & Amniotic Fluid: Flowable amnion tissue and amniotic fluid are obtained from placental products from healthy, live births. Amniotic tissue flowables contain viable cellular material and naturally occurring anti-inflammatory proteins, cytokines, growth factors, secretomes, and microRNA. Amniotic fluid contains similar components but fewer viable cells. These naturally occurring molecules are involved in cellular signaling and tissue processes.

Regenerative medicine is a cutting-edge field focused on repairing, replacing, or regenerating diseased or damaged tissues and organs using the body’s own cells. It uses stem cells, which are undifferentiated cells capable of developing into many different cell types such as muscle cells, red blood cells, or brain cells. These cells serve as a natural repair system by dividing and replenishing tissues for as long as the person is alive.

At Dynamic Stem Cell Therapy, we harvest your own cells in a minimally invasive procedure and inject them back into your body the same day.

In 2016, CNN’s Dr. Sanjay Gupta did a CNN special report in which he stated, “Stem cells are like a reserve army, awaiting activation, that contain undifferentiated or basic (“stem”) cells that can replace and rejuvenate diseased or damaged cells. This IS Regenerative Medicine.” We agree with him completely.

THE SCIENCE of How We Use Regenerative Biomolecules & CELL COMPONENTS

One of the most fundamental characteristics of cells is that they are undifferentiated, meaning they are not specialized for a single function, like red blood cells that carry oxygen or the heart, which pumps blood. Adult mesenchymal cells can differentiate into various tissue types through cell signaling with surrounding cells (paracrine function), including muscle, ligament, tendon, nerve, and blood cells.

Finally, in the realm of BioPharmacology, major advances in regenerative medical science are translating experimental models of ex vivo and in vivo expanded or differentiated cells into clinical research for the development of novel cellular therapies aimed at repairing genetically altered or damaged tissues or organs. These studies focus on the potential therapeutic applications of different tissue‐resident adult cell types and how their in vivo modulation may be relevant for addressing specific pathological disorders.

This is becoming the new era in Biologics in Regenerative Medicine, not within the scope of the current Biologic section 361 Human Tissue products (HCT/P) utilized in current therapies. This is the realm of Cell and Gene Therapies destined to become the Biologic Drugs of the future, a natural evolution of the current Biologics and the FDA regulation that we now operate within.

Cells can come from different autologous sources, such as fat or bone marrow. Many people are unaware of the potential of their own fat cells, which research is exploring for possible applications in regenerative medicine and orthobiologics.

No. We don’t use these because these are not your own cells. There is a risk of your immune system rejecting these cells. There are also ethical concerns and study findings of tumor formation.

At Dynamic Stem Cell Therapy, we use cells derived from fat and bone marrow in certain procedures. Additionally, we do PRP (platelet-rich-plasma) therapy.

Everyone is unique, so the surest way to get a good answer is to call us at (702) 547-6565. However, if you have been experiencing joint pain, have an orthopedic or sports injury, have been recommended for surgery, or are suffering from any number of diseases or other conditions, you might be a good candidate for orthobiologics.

Although the long-term effectiveness of orthobiologics has yet to be fully proven, some patients have reported improvements lasting several years. Outcomes vary based on underlying health conditions, and this procedure is not a drug or a cure for any condition.

We want you to know: therapies associated with cells are in clinical trials at this time and are not covered by any health insurance companies.

The safety and efficacy of the utilization of adult stem cells were the subject of many clinical trials before funding was severely cut in 2001. Patient funded research is still underway however, and we are very proud to be a part of this revolutionary researching process. The field of regenerative medicine is exciting and we are proud to be able to provide this right here in our United States of America.

We are happy to give military discounts to our United States armed forces and their veterans.

Most patient procedures will be completed within 3 to 4 hours.

Yes. However you will need someone to drive you to and from the office.

Yes! Post operative discomfort is minimal and there is minimal restriction on activity.

Many patients are often able to return to work the day after the procedure. Some soreness may occur for about a week following treatment. Most patients typically resume normal exercise and activity within 2 weeks, with some returning to higher-level activities in 3–4 weeks. Individual recovery times may vary depending on the patient and the procedure performed.

Individual ailments vary and the outcome of orthobiologics depends on your body’s unique healing process. Some patients have experienced results immediately or within just days of receiving orthobiologics. Other patients may take months to reach optimal resolution of their ailment. No one can guarantee the outcome for this or any treatment. Each patient is different and the results will vary.

Relatively quick and painless. Many patients have some cells taken from their body or supplied prior to the procedure, and the injection itself only takes a moment. Patients go home the same day and are usually free to return to work the next day.

Here is an example of the injection in action:

Platelet-rich plasma (PRP) is a concentration of platelets derived from your own blood. PRP contains growth factors that are being studied for their potential role in supporting tissue signaling and musculoskeletal health. It is often used as part of orthobiologic procedures to provide a patient’s own biological components during treatment.

PRP is autologous, meaning it comes from your own blood, and its potential applications are still being researched. Its use in procedures is tailored to each patient and clinician’s protocol.

We take a small amount of venous blood from you (the patient) and isolate the PRP layer. We take whole blood through sterile venipuncture for processing. Prior to the procedure the blood is transferred into a closed vacutainer tube and centrifuged to extract the PRP.

PRP (platelet-rich plasma) contains concentrated platelets from a patient’s own blood, which include growth factors. These growth factors are being studied for their potential role in supporting tissue signaling and the body’s natural cellular processes. PRP is sometimes used in regenerative medicine procedures to provide a patient’s own biological components, and research continues into how it may interact with various cell types, including those in the skin and musculoskeletal system.

Normally only 1 treatment is needed with results lasting 12-18 months.

PRP injections should not be very painful at all. On a scale of 1 to 10 where 10 is the highest, patients regularly report any pain at only a 1.

1. Skin color may appear more even or vibrant due to potential support of blood vessel activity.
2. Collagen production in the dermis could be supported, which may help improve skin texture and firmness.
3. Growth factors may help the epidermis (outer layers of skin) appear smoother by supporting normal skin maintenance.

A PRP facelift uses regenerative medicine techniques to support the body’s natural processes in the skin. Unipotent stem cells in the skin are capable of producing skin tissue, and PRP provides growth factors that may help support these cells. Each patient’s body may respond differently, and results can vary.

Potential benefits may include:

• Softer appearance of fine lines and wrinkles

• Skin that may look more refreshed, with potentially improved texture, color, and tone

PRP is similar to hyaluronic acid (HA) fillers in that it can be injected to enhance facial contours. Unlike HA fillers, PRP contains multiple growth factors that may support the body’s natural regenerative processes.

FUNCTIONS AND SPECIFIC RELATION TO THE SKIN:

PRP contains multiple growth factors that are being studied for their potential role in supporting tissue signaling and cellular activity. Some of these include:

1. Epidermal Growth Factor (EGF) – May stimulate fibroblasts and keratinocytes, supporting cellular proliferation during tissue remodeling.

2. Transforming Growth Factor (TGF) – May promote angiogenesis, influence collagen production, and support the activity of inflammatory cells.

3. Vascular Endothelial Growth Factor (VEGF) – May encourage endothelial cells to support new blood vessel formation under low-oxygen conditions.

4. Fibroblast Growth Factor (FGF) – May aid in angiogenesis, granulation, and epithelialization through supporting fibroblast, keratinocyte, and endothelial cell activity.

5. Platelet-Derived Growth Factor (PDGF) – May attract fibroblasts and macrophages to areas of tissue repair and influence collagen and proteoglycan activity.

6. Interleukins, Macrophages, keratinocytes, endothelial cells, lymphocytes, fibroblasts, osteoblasts, basophils, mast cells – Activates fibroblast differentiation. Induces collagen and proteoglycan synthesis.

7. Colony Stimulating Factors – May stimulate the proliferation of granulocytes and macrophages.

8. Keratinocyte Growth Factor (KGF) – May help fibroblasts influence keratinocyte migration, differentiation, and proliferation.

These growth factors are part of ongoing research into PRP’s potential applications for skin health, tissue repair, and regenerative medicine. Individual results may vary, and PRP is typically used as part of a clinician-directed treatment plan.

Microneedling is a minimally invasive technique that creates microchannels in the dermal layer of the skin, which can be used to deliver PRP and support collagen production. A topical anesthetic is applied before the procedure to maximize comfort. After the treatment, a cooling gel mask is applied to help soothe the skin. Many patients experience minimal discomfort during the process. For more information visit: www.dermapen.com.

We attach a one-time-use microneedle tip to a DermaPen, which is studded with tiny fine micro-needles. The microneedle gently pricks the skin, stimulating the creation of new skin cells and supporting regeneration of damaged cells. Your own PRP is then massaged into the treated skin. The procedure is intended to stimulate collagen and elastin production and support the formation of new cells. Patients may notice smoother, softer skin over time, with gradual improvements continuing for several months.

Platelet-Rich Plasma (PRP) may support rejuvenation of a patient’s facial appearance. Once processed, PRP contains a mixture of red blood cells and regenerative cells, including adult stem cells (ASCs). This composition may support collagen regeneration in the skin and potentially help improve the appearance of fine lines and wrinkles.

Yes, we can also help rejuvenate the neck and décolletage.

FDA mandates limit us. We are unable to make any sort of medical claim about expectations for success. This includes posting written patient testimonials that include such claims on our website.

However, we always appreciate when our patients post their own testimonials publicly online in places like Google, Yelp, Facebook, or Youtube. We have a consolidated patient testimonials page for our patients to reference if they wish to honor us with a review, and from there, you can easily read the existing reviews to help you in making your decision.

The FDA is set up to mandate devices and drugs only. The FDA is working diligently to be able to understand this regenerative medicine field so it can approve and regulate this therapy. Right now it is NOT designed to. We hope this changes so that they’ll be able to regulate all centers like ours in the near future! We are working hand and hand with the FDA to assure greater understanding for safe regulation of the possibilities for regenerative medicine

Politics have no place in potential therapeutics like orthobiologics and have swayed the general public as well as some of the medical community alike. It is a huge shame in our opinion, as orthobiologics has helped many of our own patients as well as numerous others the world over. We are proud to provide these advanced regenerative options at Dynamic Stem Cell Therapy in accordance with current safety standards and protocols.

The FDA recently changed its “minimal manipulation” guidelines so it is not approved at present and the FDA has given all clinics three years to adapt to the changes. As we work towards this, our protocols still follow the same day tissue transfer guidelines and “minimal manipulation” guidelines that were set forth by the FDA prior to November 2017, which are:

Your stem cells are harvested and re-administered to you on the same day within a closed system. We utilize a sterile technique for harvesting autologous stem cells. We process (extract) your cells all in the same facility to prevent contact with any outside contaminants. Our isolation procedures fall under the category of physician’s practice of medicine wherein the physician and patient are free to consider their chosen course of treatment. This is provided as a service and as a practice of medicine only. This procedure is not a drug nor do we claim it to be a cure for any condition.

Do you have any questions? Call (702) 547-6565 and we’ll be happy to speak with you!

We do not use any unethical practices at Dynamic Stem Cell Therapy, because we pride ourselves on providing ethical, proactive medicine to those it could benefit most.

The issue of ethical orthobiologics has arisen because many people believe that the human embryo is a life that justifies protection and that the extraction of embryonic stem cells is unethical. At Dynamic Stem Cell Therapy, we do not use these controversial embryonic stem cells.

Adipose orthobiologics is a minimally invasive procedure and is one of our most requested therapies. Most patients experience little to no discomfort, and the procedure can be completed within hours with minimal downtime.

Do you have any worries? Call (702) 547-6565 and we’ll be happy to answer your questions!

Orthobiologics is much more affordable than people think.

• Dynamic Stem Cell Therapy is relatively inexpensive compared to other orthobiologics clinics.
• We provide financing through our partners.
• We offer a discount to military personnel and veterans.

There is a whole lot more than most people think. You should always thoroughly research any health decision you are going to make, but it can be hard to find reliable information. To help you, we’ve not only compiled this FAQ, but we also provide a great deal of downloadable information and helpful links for you to look over. Please contact us if you have any questions!

Although the long-term effectiveness of orthobiologics has not been fully established, some patients have reported beneficial results lasting more than 10 years.