FAQ & MYTHS
Top questions and myths about cellular therapy and PRP.
Where do regenerative biomolecules come from?
SOURCES OF REPARATIVE CELLS FOR REGENERATIVE THERAPIES Cellular therapy and regenerative biomolecules reside within the cells of many tissues of the human body and for therapeutic grafting are sourced in two ways.
Autograft Tissue sourcing:
-THE AMAZING REGENERATIVE POWER OF ADIPOSE TISSUE (FAT source).
- Among other functions Adipose performs in our bodies, it plays a major role in the healing, or reparative process. Adipose contains a high concentration of important specialized reparative cells that scientists identify as Cellular therapy. Adipose also provides a cushion and support to assist in the healing process and aid the reduction of damage from injury, aging or degeneration of human tissue.
BONE MARROW ASPIRATE SOURCE
- Bone Marrow is a source used in some Regenerative procedures but it yields what most experts now consider to be an inferior cellular product with much less reparative properties. Bone marrow extraction of Stem Cells has in addition been constantly proven to be much more painful than the minimally invasive procedure of fat extraction or Allograft sourcing.
Allograft Tissue sourcing
-PERINATAL TISSUE REGENERATIVE ALLOGRAFT (PLACENTAL TISSUE SOURCE) IS CURRENTLY THE MOST EXCITING AREA OF RESEARCH IN REGENERATIVE MEDICINE
Perinatal tissue is shown by research to provide some of the most unique and potent reparative healing cells and biomolecules discovered to date and tremendous research is currently being performed in this ever-growing area of Regenerative Medical Science. Umbilical Cord tissue and Amniotic tissues and cells secrete Growth Factors and Cytokins, Exosomes, microRNA and are a viable concentration of a mixture of cells that can be easily obtained and used for Regenerative Medicine. It is used with more ease than bone marrow and adipose aspirate without the increased cost, time, inconvenience, and pain to the patient.
Perinatal Tissue Science• Flowable Amniotic Tissue & Amniotic Fluid:
Flowable Amnion tissue and Amniotic fluid are obtained from Placental products from healthy live birthed babies. Amniotic tissue flowables promote healing with viable cellular material and have anti-inflammatory properties (Cytokins & Growth Factors, Secretosomes, Exosomes, and microRNA). Amniotic Fluid alone has similar properties with fewer viable cells. These cytokines and growth factors can impact collagen and other tissue production.
DYNAMIC STEM CELL THERAPY FAQ
What is regenerative medicine?
Regenerative medicine are cells that have the potential to develop into some or many different cell types in the body. Serving as a sort of repair system, they can theoretically divide without limit to replenish other cells for as long as the person or animal is still alive. When a cell divides, each "daughter" cell has the potential to either remain a cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.
Where do cells come from?
THE SCIENCE of How We Use Regenerative Biomolecules & CELL COMPONENTS
One of the most fundamental and profound characteristics of Cells and is that they are undifferentiated. This means that they are not specialized to carry out any one specific function, like red blood cells that are designated to carry oxygen throughout the body or the heart who’s job is to pump blood. Adult Mesenchymal Cells differentiate into the tissue composition needed through cell signaling with surrounding cells (Paracrine function). In this way they can become any kind of cell your body needs, including muscle, ligament, tendon cells, as well as nerve cells and blood cells, etc.
Regenerative components including Cells and derived cellular components have been shown to be sourceable from a variety of tissue types being either Allogenic (from another human, typically Perinatal related) or Autologous (harvested from the same human patient) such as Adipose tissue or Bone Marrow Aspirate. Allogenic derived reparative products are typically harvested exclusively from umbilical cord tissue and other Placental materials and components from live healthy birthed babies. These graft materials are minimally manipulated and implanted for homologous use.The above tissue products can be grafted by utilizing a flowable micronized graft for injection or a membrane tissue graft implant (Perinatal Amniotic membrane) during open reduction or as an adjunct to arthroscopy.
Finally, in the realm of BioPharmacology, major advances in Regenerative Medical Science are translating the experimental models on ex vivo and in vivo expanded and/or differentiated cells into clinical applications for the development of novel cellular therapies aimed at repairing genetically altered or damaged tissues/organs in humans. A particular emphasis in these studies is on the therapeutic potential of different tissue‐resident adult cell types and their in vivo modulation for treating and curing specific pathological disorders.
This is becoming the new era in Biologics in Regenerative Medicine, not within the scope of the current Biologic section 361 Human Tissue products (HCT/P) utilized in current therapies. This is the realm of Cell and Gene Therapies destined to become the Biologic Drugs of the future, a natural evolution of the current Biologics and the FDA regulation that we now operate within.
What is regenerative medicine?
Cell therapy is the use of cells to treat or prevent a disease or condition. Also known as regenerative medicine, cell therapy promotes the healing of diseased, dysfunctional or injured parts of the body through the application of cells. The cells used at Dynamic Stem Cell Therapy are taken from your own body in a minimally invasive procedure and injected back into your body on the same day so that they have the potential to start healing you as soon as possible.
What is regenerative medicine?
In 2016, CNN's Dr. Sanjay Gupta did a CNN special report in which he stated,
“Stem cells are like a reserve army, awaiting activation, that contain undifferentiated or basic (“stem”) cells that can replace and rejuvenate diseased or damaged cells. This IS Regenerative Medicine.”
We agree with him completely.
What types of cells are there?
Cells can come from a few different sources, including cells that come from fat, umbilical cord cells, and bone marrow cells. Most people are unaware of the healing potential of their own fat cells, but with cell therapy, they can be used to treat all sorts of conditions.
Do you use controversial embryonic cells?
No. We don’t use these because these are not your own cells. There is a risk of your immune system rejecting these cells. There are also ethical concerns and study findings of tumor formation.
What types of cells does Dynamic Stem Cell Therapy use?
At Dynamic Stem Cell Therapy we use cells from fat. We can also use umbilical cord cells or bone marrow cells in certain circumstances. Additionally, we do PRP (platelet-rich-plasma) therapy.
Am I a good candidate for regenerative therapy?
Everyone is unique, so the surest way to get a good answer is to call us at (702) 547-6565. However, if you have been experiencing joint pain, have an orthopedic or sports injury, have been recommended for surgery, or are suffering from any number of diseases or other conditions, you might be a good candidate for cell therapy.
Is cell therapy safe?
Although cell therapy's effectiveness has yet to be proven over a very long term, beneficial results lasting 10+ years have been frequently reported across the nation. Outcomes are variable based on underlying health conditions as this procedure is not a drug or a cure for any condition.
Is cell therapy covered by health insurance?
We want you to know: therapies associated with cells are in clinical trials at this time and are not covered by any health insurance companies.
The safety and efficacy of the utilization of adult stem cells were the subject of many clinical trials before funding was severely cut in 2001. Patient funded research is still underway however, and we are very proud to be a part of this revolutionary researching process. The field of regenerative medicine is exciting and we are proud to be able to provide this right here in our United States of America.
We are happy to give military discounts to our United States armed forces and their veterans.
REGENERATIVE MEDICINE PROCEDURE HIGHLIGHTS
How long does the entire procedure take?
Most patient procedures will be completed within 3 to 4 hours.
Can I go home afterwards?
Yes. However you will need someone to drive you to and from the office.
Will I be able to return to normal activity right away?
Yes! Post operative discomfort is minimal and there is minimal restriction on activity.
How long is the recovery?
Many patients are able to go back to work on the following day. However, you may be sore for about a week following the procedure. Most patients see a return to normal exercise and activity within 2 weeks. Patients have seen a return to high level activities in as little as 3-4 weeks.
How long does it take to see improvement?
Individual ailments vary and the outcome of stem cell therapy depends on your body’s unique healing process. Some patients have experienced results immediately or within just days of receiving stem cell therapy. Other patients may take months to reach optimal resolution of their ailment. No one can guarantee the outcome for this or any treatment. Each patient is different and the results will vary.
What is getting a stem cell injection like?
Relatively quick and painless. Many patients have some cells taken from their body or supplied prior to the procedure, and the injection itself only takes a moment. Patients go home the same day and are usually free to return to work the next day.
Here is an example of the injection in action:
What is PRP and why do you use it with Stem cell therapy?
You can think of platelet-rich plasma (PRP) as the fertilizer that helps enhance regenerative medicine, since it contains important growth factors for the renewing of cells. These cells can be used to repair and rejuvenate the body.
Also autologous, PRP is essentially a fraction of your peripheral blood that can stimulate healing. Research shows that PRP activates recruited resident stem cells within your body and creates a higher likelihood of a positive response to your regenerative medicine procedure.
PRP can elicit a healing response by the use of platelets and numerous growth factors. Growth factors contained in platelet-rich plasma are directly responsible for activating autologous adipose derived stem cells and even allogenic umbilical cord stem cells. Each of the many growth factors contained play important roles in our body’s wound healing and cell regeneration.
Using PRP in effect acts as an activator of your stem cells and is essential as a medium for the stem cells to grow and proliferate in and help the cells get distributed to areas in need of repair and rejuvenation. Research has shown that high amounts of activated stem cells reintroduced back into your body can increase the likelihood of a positive response to a stem cell therapy procedure.
When elected, PRP is a critical part of the regenerative medicine services we offer.
How do you obtain the PRP?
We take a small amount of venous blood from you (the patient) and isolate the PRP layer. We take whole blood through sterile venipuncture for processing. Prior to the procedure the blood is transferred into a closed vacutainer tube and centrifuged to extract the PRP.
What is the science behind PRP?
One use of PRP for stem cell activation is for the skin. Science knows unipotent stem cells lie dormant in the skin as they provide the building blocks for healing when one sustains a burn or cut. Until recently, physicians had no convenient way to stimulate those stem cells to grow new tissue. By utilizing the growth factors found in the blood (specifically the platelets), a physician can activate the unipotent stem cells already in the skin (and other areas) and tell those cells to grow new, younger-appearing skin (or other tissue where it is directed including musculoskeletal).
How many PRP treatments are needed?
Normally only 1 treatment is needed with results lasting 12-18 months.
Are PRP injections painful?
PRP injections should not be very painful at all. On a scale of 1 to 10 where 10 is the highest, patients regularly report any pain at only a 1.
What 3 parts of the aging process can improve regarding the skin?
1. The skin color becomes a “younger” color because of new blood vessel formation.
2. New collagen formations in the dermis lift the face back to more youthful shape.
3. Because the growth factors are working to build a new dermis, the epidermis (the outer most layers of your skin) appears smoother.
What is a PRP facelift, how does it work, and what can it do for me?
During the process of a PRP face lift, regenerative medicine is used to tell the body to grow new, younger skin. There are unipotent stem cells which grow only one specific tissue, and can be found in every part of the body. For example, unipotent stem cells in the pancreas grow new pancreatic tissues. Unipotent stem cells in the skin grow new skin. Thus, our PRP facelift takes the cosmetic rejuvenation process to a whole new level.
Since your body is in control of the regeneration and rejuvenation, each patient's body will react in its own way.
Benefits could include:
Soften fine lines & wrinkles
Look refreshed & younger, with a more youthful skin texture, color & tone
How is Platelet-rich plasma (PRP) similar to Hyaluronic Acid fillers?
PRP is similar to HA because it can also be injected to sculpt the face. But, here’s the best part: not only does the PRP cause an increase in the volume, PRP contains at least 8 growth factors.
What are the 8 Growth factors contained in PRP and how can they help me?
FUNCTIONS AND SPECIFIC RELATION TO THE SKIN:
1. Epidermal Growth Factor (EGF) – Stimulates fibroblasts to secrete collagenase to degrade the matrix during the remodeling phase. Stimulates keratinocyte and fibroblast proliferation.
2. Transforming Growth Factor- Promotes angiogenesis, up-regulates collagen production and inhibits degradation, promotes chemo attraction of inflammatory cells.
3. Vascular Endothelial Growth Factor (VEGF) – Endothelial cells promote angiogenesis during tissue hypoxia.
4. Fibroblast Growth Factor (FGF) – Promotes angiogenesis, granulation, and epithelialization via endothelial cell, fibroblast, and keratinocyte migration, respectively.
5. Platelet-Derived Growth Factor (PDGF) – Attracts macrophages and fibroblasts to zone of injury. Promotes collagen and proteoglycan synthesis.
6. Interleukins, Macrophages, keratinocytes, endothelial cells, lymphocytes, fibroblasts, osteoblasts, basophils, mast cells – Activates fibroblast differentiation. Induces collagen and proteoglycan synthesis.
7. Colony Stimulating Factors – Stimulates granulocyte and macrophage proliferation.
8. Keratinocyte Growth Factor – Fibroblasts stimulate keratinocyte migration, differentiation, and proliferation.
What is microneedling?
This is a nearly painless technique to inject PRP in the dermal layer of the skin to promote facial collagen. We apply a topical anesthetic well before the procedure begins to allow you the most procedural comfort as possible (Most patients sleep throughout the process). Post procedure we apply a state of the art cooling gel mask for our patients to wear home. For more information visit: www.dermapen.com.
How exactly do you perform microneedling for facial rejuvenation?
We attach a one time use microneedle tip to a DermaPen that is studded with tiny fine “micro needles”. The microneedle gently pricks your skin stimulating the creation of new skin cells and regeneration of damaged cells. Your own PRP is then massaged into the treated skin. The goal is to stimulate the production of collagen and elastin, and the creation of new cells. Your skin will glow and immediately feel smoother and softer, with progressive improvements continuing for several months to rejuvenate.
Why do you use PRP microneedling for facial rejuvenation?
Platelet Rich Plasma can help rejuvenate a patients facial appearance. Once processed PRP has been shown to contain 50% Red Blood Cells (RBC’s) and 50% stem cells (ASC’s). This may help with regeneration of facial collagen, thus reducing the appearance of fine lines and wrinkles.
Can you microneedle anywhere else?
Yes, we can also help rejuvenate the neck and décolletage.
REGENERATIVE MEDICINE & THE FDA
Why isn’t stem cell therapy more widely advertised?
FDA mandates limit us. We are unable to make any sort of medical claim about expectations for success. This includes posting written patient testimonials that include such claims on our website.
However, we always appreciate when our patients post their own testimonials publicly online in places like Google, Yelp, Facebook, or Youtube. We have a consolidated patient testimonials page for our patients to reference if they wish to honor us with a review, and from there, you can easily read the existing reviews to help you in making your decision.
FDA regulation of Stem Cell Therapy:
The FDA is set up to mandate devices and drugs only. The FDA is working diligently to be able to understand this regenerative medicine field so it can approve and regulate this therapy. Right now it is NOT designed to. We hope this changes so that they'll be able to regulate all centers like ours in the near future! We are working hand and hand with the FDA to assure greater understanding for safe regulation of the possibilities for regenerative medicine
Politics have no place in potential therapeutics like stem cell therapy and have swayed the general public as well as some of the medical community alike. It is a huge shame in our opinion, as Stem cell therapy has helped many of our own patients as well as numerous others the world over. This is an exciting field to be a part of and we hope you choose us here at Dynamic Stem Cell Therapy for your regenerative needs.
Is the stem cell isolation procedure FDA approved?
The FDA recently changed its "minimal manipulation" guidelines so it is not approved at present and the FDA has given all clinics three years to adapt to the changes. As we work towards this, our protocols still follow the same day tissue transfer guidelines and “minimal manipulation” guidelines that were set forth by the FDA prior to November 2017, which are:
Your stem cells are harvested and re-administered to you on the same day within a closed system. We utilize a sterile technique for harvesting autologous stem cells. We process (extract) your cells all in the same facility to prevent contact with any outside contaminants. Our isolation procedures fall under the category of physician’s practice of medicine wherein the physician and patient are free to consider their chosen course of treatment. This is provided as a service and as a practice of medicine only. This procedure is not a drug nor do we claim it to be a cure for any condition.
Do you have any questions? Call (702) 547-6565 and we'll be happy to speak with you!
MYTHS & MISCONCEPTIONS
Stem cell therapy is unethical.
We do not use any unethical practices at Dynamic Stem Cell Therapy, because we pride ourselves on providing ethical, proactive medicine to those it could benefit most.
The issue of ethical stem cell therapy has arisen because many people believe that the human embryo is a life that justifies protection and that the extraction of embryonic stem cells is unethical. At Dynamic Stem Cell Therapy, we do not use these controversial embryonic stem cells. We do use adipose-derived adult stem cells and umbilical cord stem cells.
Using adult stem cells and umbilical cord stem cells does not create or promote ethical issues. With adipose stem cell therapy, you use stem cells taken from your own body to treat your own conditions. It doesn't get any better than that!
Stem cell therapy is invasive.
Adipose stem cell therapy is minimally invasive, and is one of our most sought after therapies because of it. You don't have to be anxious about pain and discomfort. You can have the entire procedure completed within hours with little to no downtime.
Do you have any worries? Call (702) 547-6565 and we'll be happy to answer your questions!
I can't afford stem cell therapy.
Stem cell therapy is much more affordable than people think.
There isn't much reputable information about stem cell therapy.
There is a whole lot more than most people think. You should always thoroughly research any health decision you are going to make, but it can be hard to find reliable information. To help you, we've not only compiled this FAQ, but we also provide a great deal of downloadable information and helpful links for you to look over. Please contact us if you have any questions!
I heard that stem cell therapy is very dangerous!
Although stem cell therapy's effectiveness has yet to be proven over a very long term, beneficial results lasting 10+ years have been frequently reported across the nation.
Page citation: NIH Stem Cell Information Home Page. In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2016 [cited April 20, 2018] Available at: https://stemcells.nih.gov/info/faqs.htm.